Answer Key Question 1: (see full question)
You Yo u selected:
A nurse is explain explaining ing to a patient about about the need to administer a loading dose of a drug. Which of the following statements best reflects the reason for administering the loading dose? "We want to mae sure that the drug becomes effecti!e faster."
Correct
Explanation:
A loading dose is recommend recommended ed for use use with drugs drugs that may tae a prolonged period to reach critical concentration so that the effects can be obtained more quicly. i#e is unrelated to the use of a loading dose. $!aluating the body%s response is not an indication for using a loading dose. &uration of action is not an indication for using a loading dose. (less ( less))
Reference:
Aschenbrenner'' &..' Aschenbrenner &..' enab enable' le' .*. Drug Therapy in th Nursing ' + ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' pp. 5+655.
Question 2:
A patient is recei!ing recei!ing 152 mg of a drug drug that has has a half6life half6life of 31 hours. ow much drug would remain after 78 hours?
(see full question)
You Yo u selected:
73.15 mg
Correct
Explanation:
Reference:
Question 3: (see full question)
You Yo u selected: Incorrect
9his amount of drug is present after 78 hours. 9his amount of drug would be present after 31 hours. 9his amount of drug would be present after 1+ hours. 9his amount of drug would b... (more ( more)) Aschenbrenner'' &..' Aschenbrenner &..' enab enable' le' .*. Drug Therapy in th Nursing ' + ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. 53. When a drug is discontinued' what percentage of that drug will remain in the body after three half6li!es? 15:
Correct response:
31.5:
Explanation:
$ach half6life remo!es 52: of the drug stored in the body. ence' after one half6life' the percentage of drug in the body would be 52:. After two half6li!es' the percentage of drug in the body would be half of 52:' which is 15:. 4onsequently' after three half6li!es' the percentage of drug would be 31.5:. (less)
Reference:
Question 4: (see full question)
You selected:
Aschenbrenner' &..' enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. 53. ;our patient is taing low dose aspirin daily for their heart. ;ou now that the patient is not recei!ing all the dosage of the aspirin that is being ingested. 9his occurs because of what? 0i!er metabolism
Incorrect
Correct response:
Explanation:
A large percentage of an oral dose is destroyed when it reaches the li!er and ne!er reaches the tissues. 9his phenomenon is nown as the first6pass effect. 9herefore =ptions A' 4' ... (more)
Reference:
Aschenbrenner' &..' enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +>.
Question 5:
9he nursing students are learning about the half6life of drugs. A student ass the instructor to explain half6life. What would be the instructor%s best response?
(see full question)
You selected:
alf6life of a drug is the time it taes for the drug to reach of its% potential pea le!el in the body.
Incorrect
Correct response:
alf6life of a drug is the time it taes for the amount of drug in the body to decrease to one6half of the pea le!el it pre!iously achie!ed.
Explanation:
9he half6life of a drug is the time it taes for the amount of
drug in the body to decrease to one6half of the pea le!el it pre!iously achie!ed. 9herefore =ptions @' 4' and & are ... (more) Reference:
Question 6: (see full question)
You selected:
Aschenbrenner' &..' enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. 53. &rugs do not metaboli#e the same in all people. n which of the following patients would a nurse expect to see an alteration in drug metabolism? A 526year6old male with cirrhosis of the li!er
Correct
Explanation:
Reference:
Question 7: (see full question)
You selected:
9he li!er is the most important site of drug metabolism. f the li!er is not functioning effecti!ely lie in patients with cirrhosis' drugs will not be metaboli#ed normally and tox... (more) Aschenbrenner' &..' enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +8. 9he nurse is explaining the pharmacoinetics of a drug being administered to a client. What is meant by the term "pharmaoinetics?" Actions of drugs
Correct
Explanation:
Reference:
,harmacoinetics refers to the actions of drugs. 9he route of administration refers to the route or method by which a medication is administered. 9reatment of o!erdoses and dosages... (more) Aschenbrenner' &..' enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +1.
Question 8: (see full question)
You selected:
9he nurse is preparing to administer a prescribed drug to a patient with a history of renal disease. 9he nurse expects a reduction in dosage based on the understanding that which of the following might be altered? Betabolism
Incorrect
Correct response:
$xcretion
Explanation:
f the idneys are not functioning properly' a drug may not be excreted properly and could accumulate in the body. Betabolism may be altered if the patient has li!er disease.... (more)
Reference:
Question 9:
Aschenbrenner' &..' enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +C. Drine acidity can play an important role in drug excretion.
(see full question)
You selected:
9rue
Correct
Reference:
Aschenbrenner' &..' enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. 52.
Question 1:
9he patient is a six6year6old who is taing 315 mg of Amoxicillin e!ery 8 hours. Assuming that the half6life of Amoxicillin is 7 hours' how much Amoxicillin would be in the child%s body at the time of the next administration of the drug?
(see full question)
You selected:
73.15 mg
Correct
Explanation:
Reference:
9he half6life of a drug is the time it taes for the amount of drug in the body to decrease to one6half of the pea le!el it pre!iously achie!ed. =ption A would occur at 7 hours af... (more) Aschenbrenner' &..' enable' .*. Drug Therapy in
Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. 53. Question 11: (see full question)
You selected:
When drugs are bound to proteins in the blood they can be transported to different areas of the body. 9he protein6drug complex is relati!ely large and cannot enter into capillaries and into tissues to react. What must occur for drugs to do their Eob in the body? 9he drug must be freed from the protein binding site
Correct
Explanation:
Reference:
Question 12: (see full question)
You selected:
Bost drugs are bound to some extent to proteins in the blood to be carried into circulation. 9he proteinFdrug complex is relati!ely large and cannot ente... ( more) Aschenbrenner' &..' enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. ++. &rugs that are highly lipid soluble are more liely to pass through the blood6brain barrier and reach the central ner!ous system. 9rue
Correct
Reference:
Question 13: (see full question)
You selected:
Aschenbrenner' &..' enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +8. =nly drugs that are lipid soluble or ha!e a transport system ha!e the ability to4ross the blood6brain barrier.
Correct
Explanation:
9he blood6brain barrier is composed of tight walls' limiting mo!ement of drug molecules. 9his barrier maes drug therapy for the 4G difficult because drug molecules cannot pass th... (more)
Reference:
Aschenbrenner' &..' enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +8.
Question 14:
A pharmacology student ass the instructor what an accurate description of a drug agonist is. What would be the instructor%s best response?
(see full question)
You selected:
A drug that interacts directly with receptor sites to cause the same acti!ity that a natural chemical would cause at that site
Correct
Explanation:
Agonists are drugs that produce effects similar to those produced by naturally occurring neurotransmitters' hormones' or other substances found in the body. Gon6 competiti!e antago... (more)
Reference:
Aschenbrenner' &..' enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. 57.
Question 15:
A client older than 85 years is more liely to experience drug reaction than a client younger than 52 years. Which of the following factors accounts for this de!elopmental !ariation?
(see full question)
You selected:
Age6related physiologic changes
Correct
Explanation:
Reference:
n older adults (85 years and older)' physiologic changes may alter all pharmacoinetic processes. Although drugs crossing the bloodFbrain barrier affect drug reaction' this ... (more) Aschenbrenner' &..' enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmcodynamics' p. +H.
Question 16: (see full question)
You selected:
Which of the following represents a pharmacoinetic phase? elect all that apply. I Betabolism I $xcretion I &istribution I Absorption
Correct
Explanation:
9he pharmacoinetic phases are absorption' distribution' metabolism' and excretion. 9he acronym A.&.B.$. is a helpful way to remember to pharmacoinetic phases.... (more)
Reference:
Aschenbrenner' &..' enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +1.
Question 17:
A nurse is to administer a drug that is loosely bound to protein. 9he nurse understands that this would mean which of the following?
(see full question)
You selected:
9he drug will lead to toxicity with other drugs.
Incorrect
Correct response:
9he drug will ha!e a short duration of action.
Explanation:
&rugs that are loosely bound to protein act !ery quicly and are excreted !ery quicly. &rugs that are tightly bound to protein are released !ery slowly. &rugs that are tightly bou... (more)
Reference:
Question 18: (see full question)
You selected: Correct
Aschenbrenner' &..' enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' pp. ++6+8. ,harmacotherapeutics is the achie!ement of the desired therapeutic goal of drug therapy. What standard does the <&A apply to a drug for appro!al? 9he drug has to be statistically significantly more effecti!e than placebo.
Explanation:
f the clinical studies indicate that the effect a drug has on the desired treatment outcome is statistically significantly better than that achie!ed with a placebo (an inacti!e su... (more)
Reference:
Aschenbrenner' &..' enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +1.
Question 19:
A drug with a half6life of + hours is administered at a dosage of 322 mg. ow much of the drug will be in the patient%s system > hours after administration?
(see full question)
You selected:
15 mg
Correct
Explanation:
Reference:
Question 2: (see full question)
You selected:
9he half6life of a drug is the time it taes for the amount of drug in the body to decrease to one6half of the pea le!el it pre!iously achie!ed. =ption A would occur 1 hours after... (more) Aschenbrenner' &..' enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. 53. 9he route medication must be gi!en to achie!e 322: bioa!ailability is gi!en.
Correct
Explanation:
Reference:
&rugs gi!en !ia the oral route' B' and sub q routes are !irtually always less than 322: a!ailable because some of the drug is absorbed in the J or li!er before reaching systemic ... (more) Aschenbrenner' &..' enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +7.
