HUBUNGAN KADAR TIMBAL (Pb) DARAH DENGAN KADAR HEMOGLOBI HEMOGLOBIN, N, HEMATOKRIT, HEMATOKRIT, DAN INDEKS ERITROSIT ERITROSIT (MCV, MCH, MCHC) PADA POLISI LALU LINTAS DI KOTA YOGYAKARTA Citra Kusuma Putri, Linda Rosita
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INTISARI
Timbal (Pb) merupakan merupakan logam berat yang dapat memberikan memberikan Latar Belakang: Timbal efek toksik jika terakumulasi dalam tubuh. Kadar Pb yang rendah sudah dapat dapat mengganggu biosintesis hemoglobin dan menyebabkan menyebabkan perubahan pada parameter hematologi lainnya. Tujuan: Tujuan penelitian ini adalah untuk mengetahui hubungan kadar Pb darah polisi lalu lintas dengan hemoglobin, hematokrit, dan indeks eritrosit (MCV, MCH, MCHC). Metode: Penelitian dilakukan secara cross-sectional pada 38 polisi lalu lintas yang bertugas bertugas di jalan raya raya kota Yogyakarta. Data dikumpulkan menggunakan menggunakan kuisioner, kadar Pb dianalisis menggunakan AAS ( Atomic Absorbtion ), dan kadar hemoglobin, hematocrit, dan indeks eritrosit Spectrophotometer ), menggunakan auto hematology analyser . Uji hipotesis menggunakan chi-square test . Hasil penelitian menunjukan kadar Pb, Hemoglobin, dan MCHC Hasil: responden dalam batas normal, 22 responden (57,9%) mengalami peningkatan Hematocrit, 8 responden (21%) memiliki nilai MCV rendah, 2 responden (5,3%) mengalami penurunan MCH. Tidak ada hubungan yang signifikan antara kadar kadar Pb dengan hemoglobin, hematocrit, MCV, MCH, MCHC, usia, lama kerja, jumlah paparan per hari, dan kebiasaan merokok (P>0,05). (P>0,05). Kesimpulan: Tidak ada hubungan antara kadar Pb dengan hemoglobin, hematocrit, dan indeks eritrosit (MCV, MCH, dan MCHC). Kata Kunci: kadar Pb darah, hemoglobin, hematocrit, MCV, MCH, MCHC, lama kerja, jumlah paparan per hari, kebiasaan merokok, polisi lalu lintas.
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CORRELATION OF BLOOD LEAD LEVEL AND HEMOGLOBIN, HEMATOCRIT AND ERYTHROCYTE INDEX (MCV, MCH, MCHC) ON TRAFFIC POLICE IN YOGYAKARTA Citra Kusuma Putri, Linda Rosita
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ABSTRACT Background: Lead (Pb) is heavy metal that have toxic effect if accumulated in human body. Low blood lead level can interrupt hemoglobin biosynthesis and can make alteration on other hematology parameter. Aim: The aim of this research is to investigate the blood lead level of traffic police and its correlation to the hemoglobin level, hematocrit, and erythrocyte index (MCV, MCH, MCHC). Methode: This research is using cross-sectional methode include 38 traffic polices who had duty at the streets throughout Yogyakarta. Data was collected by quisioner, blood lead was analized by AAS ( Atomic Absorbtion Spectrophotometer ), and hemoglobin, hematocrit, and erythrocyte index used auto hematology analyser . Hypothesis testing was conducted by chi-square test . Result: The result showed that blood lead level, hemoglobin level, and MCHC of all subject was categorized as normal. 22 subject (57,9%) had increased hematocrit, 8 subject (21%) had low level of MCV, 2 subject (5,3%) had decrease MCH. There was no significant correlation between blood lead level and hemoglobin, hematocrit, MCV, MCH, MCHC, age, leght of work, total exposure per day, and smoking habit (P>0,05). Conclusion: There was no significant correlation between blood lead level and hemoglobin, hematocrit, erythrocyte index (MCV, MCH, dan MCHC). Key Word: blood lead level, hemoglobin, hematocrit, MCV, MCH, MCHC, leght of work, total exposure per day, smoki ng habit, traffic police.
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