NEUROLOGY MCQ
1.The following are characteristics of ALS except: a.Sensory signs do not occur b.Bladder never involved c.Relentless progression inevitable d.Associated with external ophthalmoplegia
2.Following statement(s) are correct about MG: a.Is caused by antibodies to the acetylcholine receptor in the majority of cases b.Never remits spontaneously c.Should be treated by thymectomy in most young females d.Causes depression of the tendon reflexes e.May be associated with hyperthyroidism
3.Fasciculation is seen in a.Proximal myopathy b.GBS c.MND d.Hypokalemic cramps
4.Drug contraindicated in MG is a.Pyridostigmine b.Neostigmine c.Quinine
d.Ephedrine
5.A patient with motor neuron disease suddenly developed loss of emotional control and inappropriate laughing and weeping. Correct diagnosis is: a.Agitated depression b.Schizophrenia c.Pseudobulbar palsy d.SAH
6.ALS is characterized by all except a.Occurs in the 5* and
6
th
decades
b.Has signs of sensory loss c.Asymmetric d.Has fasciculation in upper limbs e.Should be differentiated from cervical cord compression
7.All are true about MND, except a.Cause is unknown b.Fasciculation is present c.UMN type paralysis in lower limbs and LMN type in upper limbs d.Loss of touch, pain and vibration sensations normal CSF
8.ALS has a.Lateral plus anterior column involvement b.Generalized convulsions are present
c.Posterior tract degeneration d.Prominent cerebellar signs
9.Earliest symptom of MG is a.Diplopia plus ptosis b.Fatigue c.Respiratory weakness d.Palatal palsy
10.All the drugs mentioned below cause peripheral neuropathy except a.INH b.Vincristine c.Methotrexate d.Emetine e.Cloxacillin
11.Albuminocytologic dissociation in CSF is seen in a.Viral meningitis b.Cervical spondylosis c.Cerebral malaria d.Infective polyneuritis
12.Mononeuritis multiplex is feature of a.PAN b.Hypersensitive vasculitis
c.Leprosy d.All of the above
13.A young man has suddenly developed paraplegia following a short febrile illness. Examination reveals lower motor neuron type paralysis with no sensory disturbances and no bladder and bowel involvement. The CSF examination in this case of likely to reveal a.Normal CSF b.Traces of blood c.Albumino-cytological dissociation d.Features of tuberculous meningitis
14.In GBS following are seen except a.CSF pleocytosis b.Areflexia c.Motor loss with paresthesia d.Ascending paralysis
15.Peripheral neuropathy is caused due to a.Bleomycin b.Busulfan c.Cisplatin d.Cyclophosphamide 16.Balaclava helmet type of sensory loss over the face is characteristic of a.Syringomyelia b.Multiple sclerosis c.Tabes dorsalis
d.All of the above
17.The neurologic disease characterized by progressive sensory loss and weakness and cavity formation within the spinal cord is called a.Multiple sclerosis b.Progressive muscular atrophy c.Gliosis d.Syringomyelia e.Amyotrophic lateral sclerosis
18.In Brown Sequard syndrome, true is a.No sensory loss b.Ipsilateral corticospinal signs c.Flexor plantar reflexes d.Contralateral flaccid paralysis
19.The commonest cause of spastic paraplegia is a.TB b.Spinal tumors c.Trauma d.Fluorosis
20.In tabes dorsalis the fibers affected are a.Lateral spinothalamic tracts b.Anterior spinothalamic tract
c.Pyramidal fibers d.Dorsal column fibers
21.In syrigomyelia, the sensation that is lost is a.Touch b.Pressure c.Pain and temperature d.Two point discrimination
22.Transverse myelitis usually affects a.Thoracic segments b.Cervical segments c.Lumbar segments d.Sacral segments
23.Which of the following is X-linked recessive a.Friedrich's ataxia b.Huntington's chorea c.Peroneal muscular dystrophy d.Duchenne muscular dystrophy
24.Myotonic muscular dystrophy is different from other dystrophies in that a.Distal muscle weakness occurs before proximal weakness b.Cranial nerve involvement occurs c.Myotonia is present
d.Cataract, frontal baldness and testicular atrophy occur e.All of the above
25.In dystrophia myotonica, untrue is a.Autosomal dominant b.Cataracts c.Mental retardation d.Always presents with myotonia e.Glucose intolerance
26.Most diagnostic test of polymyostits is a.Myogobin in urine b.Increased CPK c.EMG d.Muscle biopsy
27.In primary idiopathic polymyositis, the following group of muscles in almost never affected a.Proximal limb girdle muscles b.Pharyngeal muscles c.Extensor neck muscles d.Ocular muscles
28.Myoclonus is characterized by a.Shock like contractions b.Slow writhing irregular movements
c.Quasi purposive non repetitive movements d.Alternating movements
29.The characteristic feature of Parkinson's syndrome consist of a.Tyeraor, rigidity, hyperkinesias b.Tremor, rigidity, hypokinesia c.Rigidity, hypokinesia, tremor d.Chorea, athetosis, hypokinesia
30.Amantadine in Parkinsonism acts by\ a.Increasing dopamine level b.Decreasing cholinergic level c.Increasing norepinephrine form adrenal d.None of the above
31.Which type of Parkinsonism is most common? a.Paralysis agitans b.Post Atherosclerotic c.Post encephalitic d.Phenothiazine induced e.Cerebral tumor
32.In some patients, although walking is so difficult, they can be seen running for a bus quite well (Kinesia Paradoxa) is typically seen in a.Wilson's disease b.Cerebellar tumor
c.Parkinsonism d.Alzheimer's
33.Which of the following supports the correct diagnosis of paralysis agitans a.Oculogyric crisis b.Slow monotonous speech c.Loss of emotional control d.Bilateral extensor planter response
34.Choreiform movements, dementia in adult life and similar symptoms in family members makes the diagnosis of a.Acute chorea b.Habitspasm c.Huntington's chorea d.Dystonia musculorum deformans
35.All are true about choreal movement, except a.Irregular b.Jerky c.Present during sleep d.Quasipurposive e.Non-repetitive
36.Hemiballismus is caused by lesions of the a.Caudate nucleus b.Contralateral sub thalamic nuclei
c.Putaman d.Substantia nigra
37.The combination of polyneuritis, confusion, disorientation, loss of memory and tendency to confabulate is most likely due to a.Alcoholism b.Pernicious anemia c.Dermatomyositis d.Pellagra
38.Wemick's encephalopathy is due to deficiency of vitamin a.Bl b.B2 c.B6 d.B12
39.Korsakoff's psychosis is most often due to a.Drugs b.Head injury c.Alcoholism d.Brain tumor
40.Alzheimer's disease, which of the following neurotransmitter is mainly involved a.GABA b.5-HT
c.Dopamine d.Ach
41.One of the following is a characteristic bedside feature of Korsakoff s psychosis a.Astereognosis b.Apraxia c.Confabulation d.Hallucination
42.An 80-year old person has started forgetting the names of familiar persons and places. There has been no confabulation. He tends to forget whether he has had his meals. Clinical and neurological examination reveals no abnormality. CT scan of the bran showed symmetrical
enlargement
of
lateral
ventricles
and
diagnosis is a.Confusional state b.Alzheimer's disease c.Alcohol dementia d.Chronic Cerebrovascular insufficiency
43.Most common CNS manifestation of HTV infection is a.Acute meningitis b.Encephalopathy c.Vacuolar myelopathy d.Dementia
44.Neurocysticercosis is diagnosed by a.Pneumoencephalography
wider
sulci.
The
most
likely
b.Angiography c.EEG d.CT
45.Cysticercosis in man is characterized by except a.Commonly presents with epilepsy b.May cause hydrocephalus c.Produces an eosinophilic pleocytosis in the CSF d.Should not be treated with steroids e.May cause intermittent episodes of meningo-ehcephalitis
46.Cerebral Cysticercosis can present as following except a.Calcification on X-ray skull b.Affects meninges predominantly c.Convulsions d.Mimics cerebral tumor
47.Negri bodies are found in a.Midbrain b.Basal ganglia c.Pons d.Hippocampus
48.Food poisoning that results in motor paralysis within 24 hours is most likely due to a.Shigellosis
b.Staphylococcal toxin c.Clostridium Botulinum toxin d.Salmonellosis
49.Pseudotumor cerebri is seen in with the fallowing, except a.Gentamicin b.Tetracycline c.OCPs d.Hypervitaminosis A
50.Migraine causes the following except a.Paresthesia b.Blurring of vision c.Dysphagia d.Seizures
Answer Key
l.D 2.A.E 3.C 4.C 5.C 6.B 7.D 8.A
9.A 10.E 11.D 12.D 13.C 14.A 15.C 16.A 17.D 18.B 19.A 20.D 21.A 22.A 23.D 24.E 25.D 26.D 27.D 28.A 29.B 30.A 31.A 32.C 33.B
34.C 35.C 36.B 37.A 38.A 39.C 40.D 41.C 42.B 43.D 44.D 45.D 46.B 47.D 48.C 49.A 50.C
