Chemistry 153A: Introduction to Structure, Enzymes, and Metabolism Fall 2016
THIS COURSE IS IMPACTED! Instructor:
Dr. Heather L. Tienson:
[email protected] [email protected];; 4077A Young Hall Office Hours: Mon 9-10am, 1-2pm; Tues 1-2pm; Thurs 11-12pm
Lectures:
153A-2: 11-11:50 am MTWF CS24 153A-3: 12-12:50 pm MTWF CS24
Text:
Voet, Voet and Pratt: Fundamentals of Biochemistry, 5 Edition Purchased through www.perusall.com There is a link on the course website
Also required: Materials:
Either iClicker, iClicker2, or iClicker+, (or the REEF app for smartphones, tablets, or laptops)
Grading:
You must attend the lecture that you are enrolled in.
th
Text, Slides, Study Questions, Discussion Forum: Video casts: (
[email protected]) 2 Midterms (100 pts each) 1 Final Exam (200 pts) 5 Quizzes Homework Assignment Reading Assignments (Perusall) Clicker Responses (at least) Total:
200 200 80 30 50 25 585
https://ccle.ucla.edu/ www.bruincast.ucla.edu
Final grades will be based on your overall point total. More information about the actual ranges will be provided throughout the quarter.
I will strive to make t his class an inclusive learning community, respecting those of differing backgrounds and beliefs. As a community I expect us to be respectful to all members regardless of race, ethnicity, religion, gender, or sexual orientation. Please don’t hesitate to contact m e if you have any questions or concerns. Places to go for help when w hen you are feeling overwhelmed and need personal and/or academic assistance: you can get assistance from a counselor c ounselor in your college/dept., check out the c urrent schedule of classes under “Academic Counseling” to find the location and phone number If you are feeling stressed out o r overwhelmed contact Counseling and Psychological Services (CAPS) Wooden Center West: (310) 825-0768 www.caps.ucla.edu Center for Accessible Education; A255 Murphy Hall: (310) 825-1501, TDD (310) 206-6083 www.cae.ucla.edu Letters & Science Counseling Service A316 Murphy Hall: (310) 825-1965 www.college.ucla.edu Academics in the Commons at Covel Commons: (310) 825-9315 free workshops on a wide variety of issues relating to academic & personal success www.orl.ucla.edu (click on “academics”) College Tutorials: at Covel Commons: (310) 825-9315 free tutoring for ESL/math & science/composition/and more! www.college.ucla.edu/up/ct/ University Writing Center, Powell 228 and Humanities A61, (310) 206-1320 www.wp.ucla.edu/wc/ Lesbian, Gay, Bisexual and Transgender Resource Center Student Activities Center, B36: (310) 206-3628 www.lgbt.ucla.edu Dashew Center for International Students and Scholars 1 06 Bradley Hall: (310) 825-1681 www.internationalcenter.ucla.edu Student Legal Services A239 Murphy Hall: (310) 825 -9894 www.studentlegal.ucla.edu
Gradescope
All assignments will be graded and returned using Gradescope.com The website was developed by graduate students at Be rkeley to streamline grading of fr ee response exams. In this program we can make a specific electronic rubric that allows the TAs to grade the exams faster, more consistently and fairer. Additionally, your score breakdown will be more transparent as you will be able to see the exact rubric and exactly which points were assigned to your exam. In order to help us upload your exam accurately: 1. Write in pen 2. Write your full name at the top of every page 3. Do not write on the back of pages. You will receive an email from gradescope to set up your account when we publish the first assignment. Finally, gradescope is a secure website that is fully FERPA compliant. If you would prefer that your answers are not uploaded to gradescope please let me know and your assignments will be graded by hand.
Exams:
Quizzes:
For exams and quizzes: abbreviations are NOT ACCEPTABLE answers unless otherwise stated. Exams will be given during lecture and will include a mixture of problems similar to those in the weekly study questions (which are all previous exam questions). Each midterm will cover all the new material covered before that exam. The Final exam is cumulative, including 50% new material and 50% old material. If you are unable to take the exam at the given time, bring a written explanation of the absence prior to the exam and if the excuse is reasonable a make -up exam will be scheduled. In case of emergency bring the explanation to the next class session and a make-up exam will be scheduled. Exams must be taken within 3 working days of the scheduled date of the exam. -There will be 5 In-class quizzes given throughout the quarter. They will be at the beginning of the lecture on the days indicated. They are 10 or 20 pts each, for 80 total points. -the week before the quiz I will tell you EXACTLY what is on the quizzes. These quizzes are largely memorization and are generally given to make sure that you know basic information before we cover the material in class (i.e. glycolysis).
Homework Complete Instructions for the Protein st ructure investigation assignment will be posted on the Assignment: course website. The assignment must be submitted to gradescope by 11:59 pm on Sunday OCT th 9 . After 11:59 pm there will be 5 pts deducted from the late assignment, and 5 additional points each day after that. Regrades Regrade requests will be enabled on gradescope for 1 week after the grades for that assignment are published. You must submit a separate request for e ach question outlined in gradescope. You will have 5 regrade requests for the quarter. If your request is approved you get to keep it to use again, if it is denied you lose that one. Include a complete written explanation of the suspected mistake. Unacceptable explanations include but are not limited to: “please regrade question #__”, include why; “My answer is the same as the answer key”, tell me where they are the same. “My answer is only half the answer key, but that fully answers the question” – All points in the answer key are required for full credit. I encourage you to submit regrade requests for points that you earned that were not given. I want all the assignments to be graded accurately. The limit on regrade requests is to give you an opportunity to evaluate whether your answer does m ean same thing as the rubric.
Clickers:
Extra Credit:
1pt for answering at least 50% of the questions in a given lecture, regardless of if the answers are right or wrong. All lectures with new material will have questions. We will have 25-28 days of clicker points. There is no maximum number possible; anything after 25 is extra credit. I will have a sign in sheet if you have technical difficulties or forget your clicker.
Discussions:
Preassessment Quiz: 10 pts for completing the quiz. Will be available online. Weekly surveys: 1 pt per survey. The surveys will be open from 12pm Friday to 12pm Sunday, periodically throughout the quarter. rd Preassessment Follow-up survey: will be open during 3 week. 2 pts for completion End of the quarter Student Assessemnt of Learning Gains Survey (SALG). Instructions will be th posted during 10 week: 2 pts for completion Completing the UCLA course evaluation: 1pt This quarter in Biochemistry suggestions: (up to 5 pts). The last lecture of the quarter will highlight research related to the course that was published during the quarter. I will present papers submitted by you. Each submission can earn up to 3pts, for relevance, interest, and impact. The papers I present will earn an additional 2 pts. Instructions for selection and submission are on the course website. Submissions are due by Friday Nov 25 th at 11:59 pm.
They are not required; you may attend any discussion you wish. They will be problem solving sessions that include working through a typical exam type problem. In a given week each section will cover the same problem.
Readings at Reading assignments will be conducted via Perusall.com. On the website you will be able to ask Perusall.com: and answer questions from other students about the content of the assignment. Your “reading” will be assessed by perusal based on the t houghtfulness of your questions and answers. You will get a score for each assignment and your final point total will be based on the percentage of the possible points that you earned. There will be three types of reading assignments: Low: For your information only (i.e. you might find this really cool or interesting). These will not count towards the total possible (but can count towards your points). Medium (Med): We will rely on the basic information in these sections but will not apply the concepts in depth. SO don’t spend as much time understanding every concept. High: These are central to the course and doing well in the course depends on understanding these concepts. You don’t have to fully understand the concepts from the reading (that’s what lecture is for) but focus more of your reading time on these assignments and understanding the details and consequences of these topics. Study Questions:
These are not graded, and are for your study use only. These are all questions that have been aske d on previous 153A exams, and reflect the depth of understanding you should have for the exams.
Questions:
If you have questions that are relevant for other students regarding the running of the course or course material please check the discussion forums of the course website. If your question has not yet been asked please ask it there, as other students will likely have the same question. I will attempt to answer all questions by the nex t day.
Any instances of academic misconduct will be reported to the Dean of Students. The Academic Misconduct: consequences of this can range from failing the course to expulsion from UCLA, depending on the severity of the offense.
JUST DON’T CHEAT!!! Academic Misconduct can include, but is not limited to: Using impermissible materials on exams. You are NOT allowed the use of notes or electronic devices of any kind. The use of a calculator will be determined on an exam by exam basis. Copying answers from a fellow student. If you allow another student to copy your answer you are complicit in the misconduct. Continuing to write after time has been called. If seen your exam can be docked up to 10 pts.
Clicking answers for students that are absent.
Alternatives to Cheating: Seek out help – meet with me or your TA, ask if there is special tutoring available. Drop the course –Although 153A is impacted so this process is a bit more complicated, in extenuating circumstances you may be able to drop the course and take it during a less stressful quarter. Ask for an extension – if you explain your situation to me I will consider an extension in some cases. See a counselor at Student Psychological Services, and/or your school, college or department – UCLA has many resources for students who are feeling the stresses of academic and personal pressures (see list above). If you are stressed or feeling overwhelmed please talk to someone. All of us on campus want the best for you and are here to help you. Remember, getting caught cheating affects more than just your GPA. How will you e xplain to your parents, family and friends that you have been suspended or dismissed? How will it affect your financial aid award and/or scholarship money? Will you be required to, and be able to pay back that money if you are no longer a student? If you live in the r esidence halls, where will you go if you are told you can no longer live there? You have worked very hard to get here, If you would like mo re information, please come to the Dean o f Students’ Office in 1206 Murphy Hall, call us at (310) 825-3871 or visit our Web site at www.deanofstudents.ucla.edu. Class tips:
Form a study group. Working through problems and talking about concepts with other students will show you how well you know a concept, and help you improve your understanding: “If you can’t explain it simply, you don’t understand it well enough” – Einstein Study questions should be your main study tool for the course. They are all previous exam questions that represent the depth of understanding I expect you to have. I recommend you go through them, without looking at the answers, and tr y to work them out or answer them. If you are stuck use lecture notes, discussion sections, office hours, or the book to help you. In order to do well on the exams you should make sure that you understand the answers, not just that you have memorized them. Attempting to answer the questions in your own words, justifying the answer, or explaining it to a classmate will point out if you truly understand the concepts. Midterms cover a lot of material but can be completed in 50 minutes. I suggest you look through the exam first and pace yourself. Be sure to read the question carefully and answer the question that is being asked. It really hurts me when someone writes a true answer, but I can’t award any points because it does not answer the question!
Chemistry 153A: Lecture and Exam Schedule; FALL 2016 Date SEPT
OCT
NOV
DEC
23 26 27 28 30 3 4 5 7 10 11 12 14 17 18 19 21 24 25 26 28 31 1 2 4 7 8 9 11 14 15 16 18 21 22 23 25 28 29 30 2
Topic F M T W F M T W F M T W F M T W F M T W F M T W F M T W F M T W F M T W F M T W F
Final:
Reading (Level):
Intro Chemistry Review POGIL: Amino acids Non-covalent Interactions Protein structure Protein Structure Protein folding Ligand Binding Protein Purification Hemoglobin Carbohydrates Membranes Review MIDTERM #1 Meet the Professor Intro to Enzymes Mechanisms of Catalysis Enzyme Kinetics Enzyme Inhibition Enzyme Problems Enzyme Regulation Intro to Metabolism Metabolic Pathways and Regulation Pathway Determination techniques Glycolysis Activity Glycolysis Regulation of Glycolysis Catch-up/Review No Lecture: Veteran’s Day MIDTERM #2 PDH TCA Cycle Carbon Tracing TCA Cycle Regulation POGIL: Electron transport Chain No Lecture: Thanksgiving No Lecture: Thanksgiving Oxidative Phosphorylation ETC ATP Synthase/Integrated Regulation TQIB
Friday, December 9, 2016 11:30am-2:30pm
Quiz
Fri: (20 pt) Amino Acids
Tues: (10 pt) Carbs and Lipids
Fri:(10 pt) Enzymes
Fri: (20 pt) Glycolysis
Wed: (20 pt) TCA cycle
